Product Overview
Chloroethane CAS 75-00-3, commonly known as ethyl chloride, is a volatile organic compound (VOC) that serves as an important intermediate in chemical synthesis. At room temperature and pressure, chloroethane is a colorless, flammable gas with a characteristic ether-like odor. Its versatility as an alkylating agent and its unique physical properties make it a valuable compound across multiple industries, including pharmaceuticals, agrochemicals, and chemical manufacturing. The production and application of chloroethane require strict adherence to safety protocols due to its flammability and narcotic properties at high concentrations.
Basic Information
| CAS No. | 75-00-3 |
| UN No. | UN1037 (Ethyl chloride) |
| Molecular Formula | C₂H₅Cl |
| Hazard Classification | 2.1 (Flammable gas) |
Key Attributes & Parameters
| Purity | Available in commercial grades (typically ≥ 99.0%) and high-purity grades for synthesis. |
| Physical State | Colorless gas (compressed liquefied gas) at room temperature; can be stored as a liquid under moderate pressure or at low temperatures. |
| Boiling Point | 12.3 °C (54.1 °F) |
| Flash Point | -50 °C (-58 °F) (closed cup) |
| Key Properties | Highly volatile, flammable, slightly soluble in water, and miscible with most organic solvents. |
Features & Advantages
Versatile Alkylating Agent
Serves as an effective ethyl group donor in organic synthesis reactions (alkylation), making it a key building block for more complex molecules.
High Volatility & Quick Evaporation
Its low boiling point allows for rapid evaporation, which has historically been utilized in topical anesthetics and aerosol products.
Good Solvent Properties
Acts as a solvent for certain resins, fats, and waxes in specialized applications.
Relatively Simple Synthesis
Can be produced through established processes like hydrochlorination of ethylene or from ethanol, enabling cost-effective production.
Functional Characteristics
As a small, reactive molecule, Chloroethane CAS 75-00-3 primarily functions as an ethylating agent. In chemical reactions, it readily undergoes nucleophilic substitution (SN2 reactions), transferring an ethyl group (-C₂H₅) to nucleophiles such as oxygen, nitrogen, or sulfur atoms. This property is fundamental to its role in synthesis. It is typically handled as a liquefied gas under its own vapor pressure in pressurized cylinders. Due to its high flammability, it requires storage and use away from ignition sources in well-ventilated areas.
Primary Application Fields
Chemical Synthesis (Primary Use)
Crucial intermediate and alkylating agent in the production of tetraethyllead (historically), ethylcellulose, and various other ethyl-containing compounds.
Pharmaceutical & Agrochemical Intermediates
Used in the synthesis of certain active pharmaceutical ingredients (APIs) and agrochemicals where an ethyl group needs to be introduced.
Refrigerant & Propellant
Historically used as a refrigerant (R160) and as a propellant in aerosols, though its use has declined due to environmental and safety regulations.
Topical Anesthetic
Its rapid evaporation causes localized cooling, which numbs the skin surface; used in minor surgical procedures and sports medicine (e.g., cold sprays).
Solvent & Extractant
Used as a solvent in specific chemical processes and for extractions.
Customer Collaboration Case
A specialty chemical manufacturer developing a novel herbicide required a reliable and high-purity source of Chloroethane CAS 75-00-3 as a key ethylating agent in a critical synthesis step. The reaction required the controlled introduction of the ethyl group to a sensitive heterocyclic intermediate, and the purity of the chloroethane was crucial to avoid side reactions and maximize yield. We supplied them with a consistent batch of high-purity (≥99.5%) chloroethane and collaborated on designing a safe, automated dosing system for its controlled addition into their pressurized reactor. Our technical support ensured safe handling procedures were followed. The use of our high-purity chloroethane enabled the reaction to proceed with high selectivity, resulting in a 15% increase in yield for that step and a significant reduction in purification costs. This successful partnership allowed the customer to scale up their synthesis efficiently and secure a supply agreement for their commercial production phase.
FAQ
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